Multiple sclerosis (MS) currently has no cure, but treatments are available to help stop the progression of this central nervous system disease and manage symptoms.
As part of your MS treatment plan, you may have heard about supplements, like folate and vitamin B12, that may complement your medications and offer benefits.
Both folate (also called vitamin B9) and vitamin B12 are essential nutrients that some people may be able to get enough of from the foods they eat.
But if you have a deficiency or an underlying condition that interferes with the absorption of these nutrients, a doctor may recommend supplementation.
Read on to learn what the science says about folate and vitamin B12 for MS.
Researchers noted that such effects significantly improved both the physical and mental well-being of study participants.
It’s thought that these benefits and subsequent improved quality of life could be related to the effects of folate and B12 on homocysteine levels. While this amino acid is naturally present in the body, B vitamins can help break it down.
Additionally, vitamin B12 deficiency may lead to anemia, balance issues, and problems with the nervous system. Such symptoms are also seen in MS.
High homocysteine levels may worsen MS
In general, high homocysteine levels in the body can damage blood vessels and increase the risk of cardiovascular disease.
More research is needed to determine how such effects may play a role in humans with MS.
Let’s first take a look at what food groups naturally have these vitamins, as well as oral supplements you can take and their recommended dosages.
Natural food sources of folate
Folate is naturally present in a variety of foods, such as:
- dark leafy greens
- Brussels sprouts
- orange juice
- beef liver
Adults need about
Natural food sources of vitamin B12
Food sources of vitamin B12 include:
- beef liver
- dairy products
Vitamin B12 supplements
As a supplement, cyanocobalamin is the
When first starting a folate or vitamin B12 supplement, keep in mind that the full effects may not be seen for a few weeks. Until then, you may start experiencing slightly better energy and other improved symptoms.
In the previously mentioned
However, the exact dosage depends on your own needs, the course of your MS, and what any lab results show in terms of deficiency.
Always talk with your doctor before starting any supplements
It’s important to talk with a doctor before trying any supplements on your own. That’s particularly true for people with chronic conditions such as MS.
You’ll want to check in about the proper dosage and make sure there are no potential interactions with the medications you’re taking.
In addition to folate and vitamin B12 supplementation, you can discuss the potential of other underlying nutritional deficiencies you may have with a doctor to see whether you need to take other supplements.
One other common deficiency is vitamin D, but more studies are needed to determine whether vitamin D supplements may help MS more specifically.
Complementary practices for MS
The following complementary practices may help manage MS symptoms, but only when you work with a healthcare professional:
It’s important to talk with a doctor before starting any new supplements. They can help determine whether there’s a risk of interactions with your current MS medications and help provide correct dosing guidance.
Before you take folate supplements for MS, it’s also important that a doctor checks your vitamin B12 levels with a blood test. Folate
Research is starting to explore the possible links between certain nutritional deficiencies and related supplementation to see whether these may play a role in helping alleviate MS symptoms.
Folate and vitamin B12 supplements may help reduce homocysteine levels in the blood while increasing energy and overall well-being.
Before trying any supplements, be sure to discuss their potential benefits and risks with a doctor. They can help determine possible nutritional deficiencies and recommend supplementation as appropriate.